1000s:
Just from wikipedia:
Abbas the Great, Persia (Iran)
Ahmad the Great, Afghanistan
Akbar the Great, Indian emperor of the Mughal dynasty [3][4]
Alaric the Great, of the Visigoths
Albert the Great (aka Albertus Magnus), medieval German philosopher and theologian
Alexander the Great, King of Macedon
Alfonso the Great of León
Alfred the Great of Wessex, English
Anthony the Great early Christian saint of Egypt
Antiochus the Great, Seleucid Empire
Ashoka the Great, Indian emperor of the Maurya dynasty
Askia the Great, Mohamed Toure, Ruler of the Songhai Empire
Bhumibol Adulyadej the Great, Thailand
Boleslaus the Brave, sometimes called the Great, Poland
Buddha Yodfa Chulaloke the Great, Thailand
Canute the Great, Danish, King of Denmark, England, and Norway
Casimir the Great, Poland
Catherine the Great, Russia
Charles the Great, more commonly known as "Charlemagne"
Chulalongkorn the Great, Thailand
Constantine the Great, Rome/Byzantium
Cyrus the Great, Persia (Iran)
Darius the Great, Persia (Iran)
Donia the Great - Grote Pier, (1480-1520), Frisia
Ferdinand the Great, Castile and León
Frederick the Great, Prussia
The Great Gama, Rustam-e-Hindustan
Genghis Khan the Great, Mongolia
Gertrude the Great of Helfta, medieval mystic
Gustavus Adolphus the Great, Sweden
Gwanggaeto the Great of Goguryeo, Korea
Hanno the Great, Carthage
Henry IV the Great, France
Herod the Great, Judea
Hugh the Great, abbot of Cluny, France
Ivan the Great, Russia
John the Great, Portugal
John Paul II the Great, pope
Justinian the Great, Byzantium
Kamehameha the Great, Hawai'i
Kangxi the Great Emperor, Qing Empire
Karim Khan The Great, Persia (Iran)
Lachit Borphukan, Assam, (India)
Llywelyn the Great, Wales/Gwynedd
Louis the Great, Hungary and Poland
Louis the Great, France
Mithridates the Great, Parthia (Iran)
Mithridates the Great, Pontus
Moctezuma the Great, Aztec empire
Mubarak Al-Sabah the Great, Kuwait
Nader Shah the Great, Persia (Iran)
Napoleon the Great, France
Otto I the Great, Holy Roman Emperor
Parâkramabâhu the Great, Sri Lanka
Pacal the Great, Maya state of Palenque
Peter the Great, Russia
Peter III the Great, Aragon
Pompey the Great, Rome
Prokop the Great, Hussite leader in Bohemia
Rajaraja The Great, Indian emperor of the Cholas[5][6][7].
Ramesses the Great, Ancient Egypt
Rhodri the Great, Wales/Gwynedd
Sancho III the Great, Navarre
Sargon the Great, Akkad
Sejong the Great, Korea
Shapur the Great, Sassanid empire, Persia (Iran)
Shivaji "The Great Maratha", India
Simeon I the Great, Bulgaria
Stephen the Great, Moldova, Romania
St. Basil the Great, theologian, Cappadocia
St. Gregory the Great, pope
St. James the Great, apostle
St. Leo the Great, pope
St. Macarius the Great, Egyptian hermit
St. Nicholas the Great, pope
Taksin the Great, Thailand
Tamburlaine the Great, Timurid Empire
Theodoric the Great, Ostrogoths
Theodosius the Great, Rome
Tigranes the Great, Armenia
Umar the Great, Arab Muslim Empire
Valdemar I the Great, Denmark
Vladimir Svyatoslavich the Great, Russia
Vytautas the Great, archduke of Lithuanian Grand Duchy
William V the Great, Aquitaine
William the Great, Maleval
Wu the Great Emperor, Han Empire, China
Xerxes the Great, Persia (Iran)
Yu the Great, China
I'm sure there are 100s not listed above.